Aktuelle Publikationen

Hier konnen Sie die gesamte Liste der TKTL1-Publikationen downloaden.

A draft sequence of the Neandertal genome.
Science. 2010 May 7;328(5979):710-22.

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1alpha-induced metabolic reprograming.
Oncogene. 2010 Mar 15.

Silencing of TKTL1 by siRNA inhibits proliferation of human gastric cancer cells in vitro and in vivo.
Cancer Biol Ther. 2010 May 8;9(9).

TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization.
Clin Cancer Res. 2010 Feb 1;16(3):857-66.

Integrative Discovery of Epigenetically Derepressed Cancer Testis Antigens in NSCLC
PLoS ONE 4(12):e8189. Epub 2009 Dec 4

Glucose transporter GLUT1 expression is an stage-in dependent predictor of clinical outcome in adrenocortical carcinoma.
Endocr Relat Cancer. 2009 Sep;16(3):919-28. Epub 20 09 May 23.

Overexpression of transketolase-like gene 1 is asso ciated with cell proliferation in uterine cervix cancer.
J Exp Clin Cancer Res. 2009 Mar 30;28:43.

Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer.
PLoS ONE. 2009;4(3):e4961. Epub 2009 Mar 23.

Glycolytic phenotype in breast cancer: activation of Akt, up-regulation of GLUT1, TKTL1 and down-regulation of M2PK.
J Cancer Res Clin Oncol. 2010 Feb;136(2):219-25. Epub 2009 Aug 5.

Anaplastic nephroblastomas express transketolase-like enzyme 1.
J Clin Pathol. 2009 Jan 12.

Effects of transketolase-like gene TKTL1 on occurre nce and metastasis of human nasopharyngeal carcinoma.
Zhonghua Yi Xue Za Zhi. 2008 Dec 2;88(44):3131-4.

Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells.
Int J Cancer. 2009 Mar 15;124(6):1330-7.

Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases.
Cancer. 2008 Sep 1;113(5):936-44.

TKTL1 is overexpressed in a large portion of non-small cell lung cancer specimens.
Diagn Pathol. 2008 Aug 12;3:35.

Expression of transketolase-like 1 and activation of Akt in grade IV glioblastomas compared with grades II and III astrocytic gliomas.
Am J Clin Pathol. 2008 Jul;130(1):50-7.

Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: activation of Akt, expression of M2PK, TKTL1 and VEGF.
Eur J Obstet Gynecol Reprod Biol. 2008 Jul;139(1):72-8. Epub 2008 Apr 3.

Expression of transketolase-like 1 (TKTL1) and p-Akt correlates with the progression of cervical neoplasia.
J Obstet Gynaecol Res. 2008 Jun;34(3):293-300.

Metastasis is promoted by a bioenergetic switch: new targets for progressive renal cell cancer.
Int J Cancer. 2008 Jun 1;122(11):2422-8.

Overexpression of transketolase protein TKTL1 is as sociated with occurrence and progression in nasopharyngeal carcinoma: a potential therapeutic target in nasopharyngeal carcinoma.
Cancer Biol Ther. 2008 Apr;7(4):517-22. Epub 2008 Jan 2.

Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas.
Eur Arch Otorhinolaryngol. 2007 Dec;264(12):1431-6. Epub 2007 Jul 18.

Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells.
Cancer Lett. 2007 Aug 8;253(1):108-14. Epub 2007 Feb 23.

The TKTL1 gene influences total transketolase activity and cell proliferation in human colon cancer LoVo cells.
Anticancer Drugs. 2007 Apr;18(4):427-33.

Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer.
Oncol Rep. 2007 Apr;17(4):841-5.

Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases.
Int J Gynecol Cancer. 2007 Jan-Feb;17(1):101-6.

Expression of the mutated transketolase TKTL1, a molecular marker in gastric cancer.
Oncol Rep. 2006 Oct;16(4):657-61.

Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.
Br J Cancer. 2006 Feb 27;94(4):578-85.

Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer.
Clin Lab. 2005;51(5-6):257-73.